A comprehensive lab cookbook for creating carbohydrate modified proteins for therapeutic applications
نویسنده
چکیده
• “Glycoengineering of therapeutic proteins” focusing on how to produce tailored glycosylated versions of monoclonal antibodies as therapeutic proteins. • “Glycoanalytics” focusing on analytical characterization involving methods like mass spectroscopy and chromatographic separation to identify and profile signatures of glycosylated proteins. • “Glycoprotein complex characterization” focusing on analytical methods for epitope mapping and Ag-Ab complexes. • “PK/PD assays for therapeutic antibodies” focusing on assays to measure specific pharmacological potency readouts for glycosylated therapeutics.
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2013